HuDSeN:862

FAT4 FAT atypical cadherin 4(NM_024582.4)
CS CS23
in situ hybridisation

Data Images
HuDSeN:862
Embryo 11057, slide 20.
Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Detection Reagent
Type:in situ hybridisation probe
Identifier:FAT4
Entity Detected:FAT4, FAT atypical cadherin 4(NM_024582.4)
Sequence:nt 14350 - nt 14946 of NM_024582.4
Probe generated from:cDNA
Probe includes: ORF sequence
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:human
Carnegie Stage:CS23
Preparation:section
Expression Pattern Description
Text Annotation:
StructureLevelPatternNotes
nasal cavity
strong strong
not applicable
nasal cavity epithelium
strong strong
not applicable
Spatial Annotation:
HuDSeN:862HuDSeN:862
3D mappingspatial mapping

Annotation colour key:   strong strong       moderate moderate     weak weak         possible possible     not detected not detected
Find spatially similar expression patterns: Find spatially similar patterns
Morphological match to the template: no stars
Spatial mapping approved by: Submitter + EADHB Editor
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Principal investigator:Prof. Stephen Robertson, University of Otago, Dunedin School Medicine, University of Otago, Dunedin, New Zealand .
Submitted by:Dr. Yuzhu Cheng, Insitute of Genetic Medicine, Newcastle University, International Centre For Life, Central Parkway, Newcastle upon Tyne, UK NE1 3BZ
Experiment type:non-screen
References:PMID:24056717 Cappello S, Gray MJ, Badouel C, Lange S, Einsiedler M, Srour M, Chitayat D, Hamdan FF, Jenkins ZA, Morgan T, Preitner N, Uster T, Thomas J, Shannon P, Morrison V, Di Donato N, Van Maldergem L, Neuhann T, Newbury-Ecob R, Swinkells M, Terhal P, Wilson LC, Zwijnenburg PJ, Sutherland-Smith AJ, Black MA, Markie D, Michaud JL, Simpson MA, Mansour S, McNeill H, Götz M, Robertson SP 2013 Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development. Nat Genet (45):1300-8
Links: EMAGE same gene
  Allen Brain Atlas same gene
  BioGPS same gene

The HuDSeN Gene Expression Spatial database currently contains data from CS12 to CS23. We are in the process of upgrading the database to include fetal gene expression patterns spatially mapped into 3D models. In the meantime the fetal gene expression images are available to view here.


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