HuDSeN:620

FOXP2 forkhead box P2(NM_014491)
CS CS22
in situ hybridisation

Data Images
HuDSeN:620 HuDSeN:620 HuDSeN:620 HuDSeN:620 HuDSeN:620
Embryo N4, section 107. Embryo N4, section 047. Embryo N4, section 057. Embryo N4, section 068. Embryo N4, section 075.
HuDSeN:620 HuDSeN:620 HuDSeN:620 HuDSeN:620 HuDSeN:620
Embryo N4, section 097. Embryo N4, section 116. Embryo N4, section 122. Embryo N4, section 146. Embryo N4, section 155.
HuDSeN:620 HuDSeN:620 HuDSeN:620 HuDSeN:620 HuDSeN:620
Embryo N4, section 164. Embryo N4, section 175. Embryo N4, section 187. Embryo N4, section 197. Embryo N4, section 206.
HuDSeN:620 HuDSeN:620 HuDSeN:620
Embryo N4, section 216. Embryo N4, section 227. Embryo N4, section 231.
Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes
The experimental slides are from a late CS21 embryo mapped to the CS22 model.
Detection Reagent
Type:in situ hybridisation probe
Identifier:FOXP2
Entity Detected:FOXP2, forkhead box P2(NM_014491)
Sequence:nt 2825 - nt 3376 of NM_014491
Probe generated from:cDNA
Probe includes: 3' UTR sequence
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:human
Carnegie Stage:CS22
Preparation:section
Expression Pattern Description
Text Annotation:
StructureLevelPatternNotes
cerebral cortex
moderate moderate
not applicable
diencephalon
moderate moderate
not applicable
cerebellum primordium
strong strong
not applicable
future corpus striatum
moderate moderate
not applicable
medulla oblongata
possible possible
not applicable
spinal cord
possible possible
not applicable
midbrain
weak weak
not applicable
Spatial Annotation:
HuDSeN:620HuDSeN:620HuDSeN:620HuDSeN:620HuDSeN:620
3D mapping3D mapping3D mapping3D mapping3D mapping
HuDSeN:620HuDSeN:620HuDSeN:620HuDSeN:620HuDSeN:620
3D mapping3D mapping3D mapping3D mapping3D mapping
HuDSeN:620HuDSeN:620HuDSeN:620HuDSeN:620HuDSeN:620
3D mapping3D mapping3D mapping3D mapping3D mapping
HuDSeN:620HuDSeN:620HuDSeN:620HuDSeN:620HuDSeN:620
3D mapping3D mapping3D mapping3D mappingspatial mapping

Annotation colour key:   strong strong       moderate moderate     weak weak         possible possible     not detected not detected
Find spatially similar expression patterns: Find spatially similar patterns
Morphological match to the template: three stars
Spatial mapping approved by: Submitter + EADHB Editor
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Principal investigator:Prof. Andrew Copp, Institute of Child Health, Neural Development Unit, 30 Guilford Street,, London, UK WC1N 1EH
Submitted by:Yuzhu Cheng, Insitute of Human Genetics, Newcastle University, International Centre For Life, Central Parkway, Newcastle upon Tyne, UK NE1 3BZ
Experiment type:non-screen
References:PMID:12876151 Lai CS, Gerrelli D, Monaco AP, Fisher SE, Copp AJ 2003 FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder. Brain (126):2455-62
Links: EMAGE same gene
  Allen Brain Atlas same gene
  BioGPS same gene

Entries are submitted to the HuDSeN database using the official gene name, according to the HUGO Gene Nomenclature Committee, at the time of uploading. If an official gene name subsequently changes after submission of the entry to the database, the previous name may be shown in the table above.


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