HuDSeN:846

FAT4 FAT atypical cadherin 4(NM_024582.4)
CS 11PCW
in situ hybridisation

Data Images
HuDSeN:846
1173_11pcw
Expression pattern clarity: no stars
Notes
Expression is seen in the developing cerebral cortex and choroid plexus.
Detection Reagent
Type:in situ hybridisation probe
Identifier:FAT4
Entity Detected:FAT4, FAT atypical cadherin 4(NM_024582.4)
Sequence:nt 14350 - nt 14946 of NM_024582.4
Probe generated from:cDNA
Probe includes: ORF sequence
Notes:Please add any additional information here if you cannot entirely define the probe sequence using the above method
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:human
Carnegie Stage:11PCW
Preparation:section
Expression Pattern Description
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + NBT/BCIP
General Information
Principal investigator:Prof. Stephen Robertson, University of Otago, Dunedin School Medicine, University of Otago, Dunedin, New Zealand
Submitted by:Dr. Yuzhu Cheng, Insitute of Genetic Medicine, Newcastle University, International Centre For Life, Central Parkway, Newcastle upon Tyne, UK NE1 3BZ
References:PMID:24056717 Cappello S, Gray MJ, Badouel C, Lange S, Einsiedler M, Srour M, Chitayat D, Hamdan FF, Jenkins ZA, Morgan T, Preitner N, Uster T, Thomas J, Shannon P, Morrison V, Di Donato N, Van Maldergem L, Neuhann T, Newbury-Ecob R, Swinkells M, Terhal P, Wilson LC, Zwijnenburg PJ, Sutherland-Smith AJ, Black MA, Markie D, Michaud JL, Simpson MA, Mansour S, McNeill H, Götz M, Robertson SP 2013 Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development. Nat Genet (45):1300-8
Links: EMAGE same gene
  Allen Brain Atlas same gene
  BioGPS same gene

The HuDSeN Gene Expression Spatial database currently contains data from CS12 to CS23. We are in the process of upgrading the database to include fetal gene expression patterns spatially mapped into 3D models. In the meantime the fetal gene expression images are available to view here.


Copyright ©The Medical Research Council & University of Newcastle
All Rights Reserved.